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HBA-IMSI

Two-stage sperm selection – intra-cytoplasmic injection of morphologically selected sperm into the egg (IMSI), complemented by sperm selection using hyaluronan (HBA) medium.

What is HBA-IMSI – two-stage sperm selection

HBA-IMSI is a combination of IMSI and HBA, i.e. the morphological selection of the sperm under very high magnification (IMSI) with the receptor reaction of its head with hyaluronan (PICSI/HBA).

IMSI

The selection of spermatozoa with the optimal morphological structure is performed using the highest quality Nomarski contrast optics, supported by special software and the expertise of a highly qualified clinical embryologist. IMSI can identify very subtle abnormalities in the structure of the sperm head, which are invisible during standard IVF.

PICSI/ HBA

Sperm selected by the IMSI technique are re-selected based on their ability to bind to hyaluronan via head surface receptors. The sperm selected in this way is very likely to be biologically mature and functional. This can increase the chance of the egg fertilising, producing a normal embryo and developing pregnancy, and reduce the risk of miscarriage.

Two-stage sperm selection offers the chance to obtain better embryological results and achieve pregnancy in patients with failures in previous treatment attempts.

Examples of indications for the use of HBA-IMSI two-stage sperm selection:

history of miscarriage, including that associated with male factor,
severe teratozoospermia (sperm morphology 0–1%),
abnormal sperm chromatin together with abnormal sperm morphology,
previous unsuccessful attempts to achieve pregnancy with ICSI and IMSI (few developing embryos, low quality embryos, no blastocysts, no implantation).

Remember that infertility is a disease in which you need proper diagnosis and the help of specialized doctors. See for yourself that the first visit to the fertility clinic is not a reason to be ashamed, but the first step towards fulfilling the dream of conceiving a child.

Prof. MD, PhD

Jerzy Radwan

specialist in gynaecological endocrinology and reproduction
specialist in gynaecology and obstetrics

First visit

Prepare accordingly for your first visit. For your first appointment with the doctor, please bring with you:

The woman’s age is between 20 and 40 years old and, on biochemical and ultrasound assessment, there is a chance that she has induced multiple ovulation (AMH above 0.7 ng/ml at least three follicles in the ovary)
Are married or in a civil partnership (according to the definition of civil partnership donation set out in Article 2(1)(8) of the Act of 25 June 2015 on Infertility Treatment
Have a place of residence in the area of Lodz on the day of qualification for the programme
Couples with cancer in whom gamete or embryo freezing is used to preserve fertility are eligible for rapid qualification.

Choose clinic for your first visit

Clinic in Bydgoszcz

Ogińskiego 2

Clinic in Gdynia

ul. Św. Piotra 21

Clinic in Kielce

Podzamcze 45, Chęciny

Clinic in Lodz

Rudzka 34/36, Rzgów

Clinic in Warsaw

ul. Cybernetyki 7 (Helion building)

Clinic in Wroclaw

Diagnosed infertility is often a shock and causes a significant decrease in the mental condition, which is why mental care for a couple trying for a child is extremely important.

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