Early diagnostics of genetic diseases and defects PGD-NGS (PGT-M)

Preimplantation Genetic Testing for Monogenic/Single Gene Defects (PGD, PGT-M) is a form of genetic testing that allows the couples with an increased risk of single gene defects to examine the embryos before their transfer to the uterus. PGD (PGT-M) is performed in conjunction with IVF.

PGD (PGT-M) can be performed for any known, inherited, single gene, including autosomal recessive genes (e.g. cystic fibrosis), autosomal dominant genes (e.g. Huntington’s disease), or other genetic disorders.

PGD (PGT-M) comprises molecular tests of the blastomeres collected from the embryo, and helps to identify the embryos without genetic defects for the intrauterine transfer.

The complete PGD (PGT-M) procedure involves a few stages:

  • analysis of the clinical status
  • development of a proper genetic test
  • in-vitro fertilization,
  • embryonic biopsy
  • genetic diagnostics (PGT-M)
  • embryotransfer