• Our staff participated in the development of the first successful procedure of in vitro fertilisation in Poland (Białystok 1987) and created the first in Lodz, and the second in Poland, IVF treatment centre.
  • Gameta was the first infertility clinic in Europe certified by the European Society for Human Reproduction and Embryology (ESHRE) as a centre for infertility treatment and research.
  • Gameta Group is the longest operating and largest network of medically assisted procreation centres in Poland with one of the greatest scientific contributions.

We are the pioneers in using groundbreaking methods of medically assisted procreation in Poland:

  • We have an electronic system to prevent mistakes – RI Witness.
  • We were the first in Poland to introduce into clinical practice the vitrification freezing of germ cells and embryos.
  • We were the first in Poland to successfully transplant ovarian tissue.
  • We were one of the first in Poland to achieve pregnancy from an egg fertilised with sperm taken directly from the testicles.
  • We were the first in Poland to introduce observation of embryos in low oxygen concentrations.
  • We were the first in Poland to introduce the technique of continuous observation of embryos (time-lapses).
  • We established the first oocyte bank in Poland.

Our team

  • Over a dozen specialists in gynaecological and reproductive endocrinology,
  • Several ESHRE clinical embryologists,
  • Regional consultant (Łódź) in gynaecological endocrinology and reproduction,
  • European Society for Human Reproduction and Embryology expert supervising the accreditation of medically assisted procreation centres in Europe,
  • Chairman of the Fertility and Infertility Section of the Polish Society of Gynaecologists and Obstetricians.

We are:

  • Accredited to provide postgraduate training for doctors in the specialisation: Gynaecological Endocrinology and Reproduction
  • Accredited by the Minister of Health to provide initial and continuing training for doctors, embryologists and nurses in medically assisted procreation procedures.

Gameta Clinic conducts research and development work, and is a beneficiary of Regional and National Operational and Scientific Programmes

  • “Development of an R&D laboratory for the development of effective methods for securing the procreative capacity of the population”
  • “Development of an R&D laboratory for the development of effective infertility treatments for patients with spinal cord injuries”
  • “Development of R&D laboratory for regenerative medicine in assisted reproduction”

We collaborate with

  • The Institute of Occupational Medicine in Łódź
  • The Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences – Scientific Consortium
  • The Regional Science and Technology Centre in Chęciny
  • The Medical University of Gdańsk
  • Bioarray – Alicante Science and Technology Park

Scientific papers published by our team are cited in more than 1800 textbooks and renowned scientific journals (data from Scopus 2021 database).

GAMETA - zespól roboczy

Key scientific publications: located in the abdo:

Radwan P, Wielgomas B, Radwan M, Krasiński R, Klimowska A, Zajdel R, Kaleta D, Jurewicz J. Triclosan exposure and in vitro fertilization treatment outcomes in women undergoing in vitro fertilization. Environ Sci Pollut Res Int. 2021 Mar;28(10):12993-12999. doi: 10.1007/s11356-020-11287

Czubacka E, Wielgomas B, Klimowska A, Radwan M, Radwan P, Karwacka A, Kałużny P, Jurewicz J. Urinary Bisphenol A Concentrations and Parameters of Ovarian Reserve among Women from a Fertility Clinic. Int J Environ Res Public Health. 2021 Jul 29;18(15):8041. doi: 10.3390/ijerph18158041. PMID: 34360336; PMCID: PMC8345502.

Jurewicz J, Radwan P, Wielgomas B, Radwan M, Karwacka A, Kałużny P, Piskunowicz M, Dziewirska E, Hanke W. Exposure to pyrethroid pesticides and ovarian reserve. Environ Int. 2020 Nov;144:106028. doi: 10.1016/j.envint.2020.106028.

Radwan P, Wielgomas B, Radwan M, Krasiński R, Klimowska A, Kaleta D, Jurewicz J. Urinary bisphenol A concentrations and in vitro fertilization outcomes among women from a fertility clinic. Reprod Toxicol. 2020 Jul 25;96:216-220. doi: 10.1016/j.reprotox.2020.07.009.

Wilczyńska K, Radwan P, Krasiński R, et al. KIR and HLA-C genes in male infertility. J Assist Reprod Genet. 2020;10.1007/s10815-020-01814-6. doi:10.1007/s10815-020-01814-6

Jurewicz J, Radwan M, Wielgomas B, et al. Parameters of ovarian reserve in relation to urinary concentrations of parabens. Environ Health. 2020;19(1):26. Published 2020 Mar 2. doi:10.1186/s12940-020-00580-3

Nowak I, Wilczyńska K, Radwan P, et al. Association of Soluble HLA-G Plasma Level and HLA-G Genetic Polymorphism With Pregnancy Outcome of Patients Undergoing in vitroFertilization Embryo Transfer. Front Immunol. 2020;10:2982. Published 2020 Jan 14. doi:10.3389/fimmu.2019.0298

Zimmer M, Pomorski M, Kamiński P, et al. Polish Society of Gynecologists and Obstetricians Guidelines for the application of hysteroscopy in gynecology. Ginekol Pol. 2019;90(8):482‐489. doi:10.5603/GP.2019.0083

Jurewicz J, Wielgomas B, Radwan M, et al. Triclosan exposure and ovarian reserve. Reprod Toxicol. 2019;89:168‐172. doi:10.1016/j.reprotox.2019.07.086

Dziewirska E, Radwan M, Wielgomas B, et al. Human Semen Quality, Sperm DNA Damage, and the Level of Urinary Concentrations of 1N and TCPY, the Biomarkers of Nonpersistent Insecticides. Am J Mens Health. 2019;13(1):1557988318816598. doi:10.1177/1557988318816598

Jurewicz J, Dziewirska E, Radwan M, Hanke W. Air pollution from natural and anthropic sources and male fertility. Reprod Biol Endocrinol. 2018;16(1):109. Published 2018 Dec 23. doi:10.1186/s12958-018-0430-2

Radwan M, Wielgomas B, Dziewirska E, et al. Urinary Bisphenol A Levels and Male Fertility. Am J Mens Health. 2018;12(6):2144‐2151. doi:10.1177/1557988318799163

Zamkowska D, Karwacka A, Jurewicz J, Radwan M. Environmental exposure to non-persistent endocrine disrupting chemicals and semen quality: An overview of the current epidemiological evidence. Int J Occup Med Environ Health. 2018;31(4):377‐414. doi:10.13075/ijomeh.1896.01195

Bylińska A, Wilczyńska K, Malejczyk J, et al. The impact of HLA-G, LILRB1 and LILRB2 gene polymorphisms on susceptibility to and severity of endometriosis. Mol Genet Genomics. 2018;293(3):601‐613. doi:10.1007/s00438-017-1404-3

Nowak I, Bylińska A, Wilczyńska K, et al. The methylenetetrahydrofolate reductase c.c.677 C>T and c.c.1298 A>C polymorphisms in reproductive failures: Experience from an RSA and RIF study on a Polish population. PLoS One. 2017;12(10):e0186022. Published 2017 Oct 26. doi:10.1371/journal.pone.0186022

Karwacka A, Zamkowska D, Radwan M, Jurewicz J. Exposure to modern, widespread environmental endocrine disrupting chemicals and their effect on the reproductive potential of women: an overview of current epidemiological evidence. Hum Fertil (Camb). 2019;22(1):2‐25. doi:10.1080/14647273.2017.135882

Algorytmy diagnostyczno-lecznicze w zastosowaniu do niepłodności pod redakcją prof. dr hab. n. med. Sławomira Wołczyńskiego, dr n. med. Michała Radwana

Jurewicz J, Radwan M, Wielgomas B, et al. Human Semen Quality, Sperm DNA Damage, and the Level of Reproductive Hormones in Relation to Urinary Concentrations of Parabens. J Occup Environ Med. 2017;59(11):1034‐1040. doi:10.1097/JOM.0000000000001106

Nowak I, Wilczyńska K, Wilczyński JR, et al. KIR, LILRB and their Ligands’ Genes as Potential Biomarkers in Recurrent Implantation Failure. Arch Immunol Ther Exp (Warsz). 2017;65(5):391‐399. doi:10.1007/s00005-017-0474-6

Jach R, Pabian W, Spaczyński R, et al. Recommendations of the Fertility Preservation Working Group in Oncological, Hematological and Other Patients Treated With Gonadotoxic Therapies „ONCOFERTILITY” (GROF) of the Polish Society of Oncological Gynecology. J Adolesc Young Adult Oncol. 2017;6(3):388‐395. doi:10.1089/jayao.2017.0039

Radwan P, Abramik A, Wilczyński J, Radwan M. Successful autotransplantation of cryopreserved ovarian tissue with recovery of the ovarian function. Ginekol Pol. 2016;87(3):235‐240. doi:10.17772/gp/61981

Jurewicz J, Radwan M, Sobala W, et al. Exposure to widespread environmental endocrine disrupting chemicals and human sperm sex ratio. Environ Pollut. 2016;213:732‐740. doi:10.1016/j.envpol.2016.02.00

Jurewicz J, Radwan M, Sobala W, et al. Dietary Patterns and the Frequency of Disomy in Human Sperm. Urology. 2016;93:86‐91. doi:10.1016/j.urology.2016.03.02

Jurewicz J, Radwan M, Sobala W, Radwan P, Bochenek M, Hanke W. Dietary Patterns and Their Relationship With Semen Quality. Am J Mens Health. 2018;12(3):575‐583. doi:10.1177/1557988315627139

Radwan M, Jurewicz J, Polańska K, et al. Exposure to ambient air pollution–does it affect semen quality and the level of reproductive hormones?. Ann Hum Biol. 2016;43(1):50‐56. doi:10.3109/03014460.2015.1013986

Radwan M, Jurewicz J, Sobala W, et al. Human sperm aneuploidy after exposure to polycyclic aromatic hydrocarbons [published online ahead of print, 2015 Mar 10]. Reprod Fertil Dev. 2015;10.1071/RD14063. doi:10.1071/RD14063

Radwan M, Jurewicz J, Radwan P, Ulańska A, Jakubowski L, Hanke W. Occupational risk factors and frequency of sex chromosome disomy. Hum Fertil (Camb). 2015;18(3):200‐207. doi:10.3109/14647273.2015.1006693

Radwan M, Jurewicz J, Radwan P, Ulańska A, Jakubowski L, Hanke W. Occupational risk factors and frequency of sex chromosome disomy. Hum Fertil (Camb). 2015;18(3):200‐207. doi:10.3109/14647273.2015.1006693

Radwan M, Jurewicz J, Wielgomas B, et al. The association between environmental exposure to pyrethroids and sperm aneuploidy. Chemosphere. 2015;128:42‐48. doi:10.1016/j.chemosphere.2014.12.077

Radwan P, Radwan M, Kozarzewski M, Polac I, Wilczyński J. Evaluation of sonohysterography in detecting endometrial polyps – 241 cases followed with office hysteroscopies combined with histopathological examination. Wideochir Inne Tech Maloinwazyjne. 2014;9(3):344‐350. doi:10.5114/wiitm.2014.43024

Jurewicz J, Radwan M, Sobala W, et al. Lifestyle factors and sperm aneuploidy. Reprod Biol. 2014;14(3):190‐199. doi:10.1016/j.repbio.2014.02.002

Jurewicz J, Radwan M, Sobala W, et al. The relationship between exposure to air pollution and sperm disomy. Environ Mol Mutagen. 2015;56(1):50‐59. doi:10.1002/em.21883

Skweres T, Wójcik D, Ciepłuch R, Sliwiński W, Czech R, Gruszczyński W, Rogacki M. Thyroid dysfunction during severe ovarian hyperstimulation syndrome. A case report. Ginekol Pol. 2014 Jun;85(6):472-5. doi: 10.17772/gp/1756. PMID: 25029815.

Radwan P, Krasiński R, Radwan M, Połać I. An ongoing twin pregnancy after embryo time laps monitoring in a patient with a history of IVF failures–case report and literature review]. Ginekol Pol. 2014;85(4):304‐308. doi:10.17772/gp/1728

Radwan P, Radwan M, Kobielska L, Sikora J. Live birth of monochorionic triamniotic triplets after in vitro fertilization and blastocyst transfer: case report and review of the literature. Ginekol Pol. 2014;85(2):154‐157. doi:10.17772/gp/1707

Jurewicz J, Radwan M, Sobala W, Radwan P, Bochenek M, Hanke W. Effects of occupational exposure – is there a link between exposure based on an occupational questionnaire and semen quality?. Syst Biol Reprod Med. 2014;60(4):227‐233. doi:10.3109/19396368.2014.907837

Jurewicz J, Radwan M, Sobala W, et al. Association between a biomarker of exposure to polycyclic aromatic hydrocarbons and semen quality. Int J Occup Med Environ Health. 2013;26(5):790‐801. doi:10.2478/s13382-013-0152-9

Radwan P, Radwan M, Polać I, Wilczyński JR. Detection of intracavitary lesions in 820 infertile women: comparison of outpatient hysteroscopy with histopathological examination. Ginekol Pol. 2013;84(10):857‐861. doi:10.17772/gp/1652

Radwan, P., Krasinski, R., Chorobik, K., & Radwan, M. (Morphokinetics and time-lapse technique as a predictor of embryo development to the blastocyst stage. Human Reproduction, 2013 28.

Jurewicz J, Radwan M, Sobala W, et al. Human urinary phthalate metabolites level and main semen parameters, sperm chromatin structure, sperm aneuploidy and reproductive hormones. Reprod Toxicol. 2013;42:232‐241.

Radwan, P., Polac, I., Borowiecka, M., Bijak, M., & Radwan, M. (Developmental potential of human oocytes undergoing IVF in the presence of oxidative stress markers. Human Reproduction, 2013. 26.

Radwan P, Radwan M, Połać I, Lewkowicz P, Wilczyński JR. IL-18 and IL-18 binding protein concentration in ovarian follicular fluid of women with „tubal factor” subjected to in vitro fertilization. Postepy Hig Med Dosw (Online). 2013;67:463‐470. Published 2013 May 21. doi:10.5604/17322693.1050036

Wilczyński JR, Radwan P, Tchórzewski H, Banasik M. Immunotherapy of patients with recurrent spontaneous miscarriage and idiopathic infertility: does the immunization-dependent Th2 cytokine overbalance really matter?. Arch Immunol Ther Exp (Warsz). 2012;60(2):151‐160. doi:10.1007/s00005-012-0161-6

Basta A, Brucka A, Górski J, Kotarski J, Kulig B, Oszukowski P, Poreba R, Radowicki S, Radwan J, Sikora J, Skret A, Skrzypczak J, Szyłło K; Polish Gynocologic Society Experts Group. Stanowisko Zespołu Ekspertów Polskiego Towarzystwa Ginekologicznego dotyczace diagnostyki i metod leczenia endometriozy [The statement of Polish Society’s Experts Group concerning diagnostics and methods of endometriosis treatment]. Ginekol Pol. 2012 Nov;83(11):871-6. Polish. PMID: 23379199

Fulmańska M, Radowicka M, Radwan M, Kalinka J. Ciaza u 47-letniej kobiety poddanej zabiegowi pozaustrojowego zapłodnienia z zastosowaniem komórki jajowej pobranej od dawczyni (IVF-OD) [Pregnancy of a 47-year old woman treated by in vitro fertilization using oocyte from a donor (IVF-OD)]. Ginekol Pol. 2011;82(5):378‐381

Vlaisavljević V, Meden-Vrtovec H, Lewandowski P, et al. An observational study of assisted reproductive technology outcomes in new European Union member states: an overview of protocols used for ovarian stimulation. Curr Med Res Opin. 2010;26(4):819‐825. doi:10.1185/03007990903577118

Jurewicz J, Hanke W, Radwan M, Bonde JP. Environmental factors and semen quality. Int J Occup Med Environ Health. 2009;22(4):305‐329. doi:10.2478/v10001-009-0036-1

Radwan, P., Radwan, M., Polac, I., & Wilczynski, J. R. (2010). Hysteroscopy-a technique for everyone and everywhere. 1074 outpatient hysteroscopies. Przeglad Menopauzalny, 14(2),101.

Jurewicz J, Hanke W, Sobala W, Merecz D, Radwan M. Wpływ stresu zawodowego na jakość nasienia [The effect of stress on the semen quality]. Med Pr. 2010;61(6):607‐613.

Borowiecka M, Polac I, Nowak P, Radwan P, Ponczek MB, Wachowicz B. Changes in hemostatic parameters after oral hormone therapy in postmenopausal women. J Womens Health (Larchmt). 2010;19(12):2267‐2270. doi:10.1089/jwh.2010.2040

Sipak-Szmigiel O, Cybulski C, Wokołorczyk D, et al. HLA-G polymorphism and in vitro fertilization failure in a Polish population. Tissue Antigens. 2009;73(4):348‐352. doi:10.1111/j.1399-0039.2008.01205.x

Wilczynski JR, Kalinka J, Radwan M. The role of T-regulatory cells in pregnancy and cancer. Front Biosci. 2008;13:2275‐2289. Published 2008 Jan 1. doi:10.2741/284

Popiela TJ, Wicherek L, Radwan M, et al. The differences in RCAS1 and DFF45 endometrial expression between late proliferative, early secretory, and mid-secretory cycle phases. Folia Histochem Cytobiol. 2007;45 Suppl 1:S157‐S162.

Wilczynski JR, Radwan M, Kalinka J. The characterization and role of regulatory T cells in immune reactions. Front Biosci. 2008;13:2266‐2274. Published 2008 Jan 1. doi:10.2741/2840

Kalinka J, Radwan M. The impact of dydrogesterone supplementation on serum cytokine profile in women with threatened abortion. Am J Reprod Immunol. 2006;55(2):115‐12

Radwan J, Bielak A, Niwald W, Pawlicki J, Banaszczyk R, Makuła D. Test po stosunku oceniany w płynie otrzewnowym [Postcoital test evaluated in peritoneal fluid]. Ginekol Pol. 1995 Apr;66(4):228-30. Polish. PMID: 8529940.

Radwan J, Pawlicki J, Bastit P. Niepłodność meska wywołana brakiem akrosomu w plemnikach z okragła główka [Male sterility caused by a lack of the acrosome in spermatozoa with a round shaped head]. Ginekol Pol. 1994 Sep;65(9):537-40. Polish. PMID: 7721169.

Radwan J, Kulikowski M, Kuczyński W, Sola E, Wołczyński S, Szamatowicz M. Wykrywanie przeciwciał przeciwplemnikowych technika immunokuleczek (IBA) w nasieniu z autoaglutynacja [Detection of anti-spermatozoa antibodies by the immunobead assay (IBA) in sperm autoagglutination]. Ginekol Pol. 1988 Oct;59(10):628-31. Polish. PMID: 3248755.

Kulikowski M, Kuczyński W, Radwan J, Sola E, Wołczyński S, Szamatowicz M. Pozaustrojowe zapłodnienie–przeniesienie zarodka (IVF-ET). II. Sekrecja progesteronu, estradiolu i testosteronu przez kompleks “oocyt–corona radiata–cumulus” w hodowli in vitro w czasie pozaustrojowego zapłodnienia [Fertilization in vitro–embryo transfer (IVF-ET). II. Secretion of progesterone, estradiol and testosterone by the “oocyte-corona radiata-cumulus” complex in the in vitro culture during in vitro fertilization]. Ginekol Pol. 1988 May;59(5):245-9. Polish. PMID: 32348

Szamatowicz M, Kuczyński W, Kulikowski M, Radwan J, Sola E, Wołczyński S. Pozaustrojowe zapłodnienie–przeniesienie zarodka (IVF-ET). V. Analiza wyników realizacji i etapu programu pozaustrojowego zapłodnienia w Instytucie Połoznictwa i Chorób Kobiecych w Białymstoku [Fertilization in vitro–embryo transfer (IVF-ET). V. Analysis of the results of the first stage of the in vitro fertilization program of the Institute of Obstetrics and Gynecologic Diseases in Białystok]. Ginekol Pol. 1988 May;59(5):263-8. Polish. PMID: 3234868.